10F2

Murine          IgM
Primary            7541621
Whole virus DENV-2
Whole virus DENV-2, neutralizing
       
E protein epitope map
E protein epitope map description
This epitope map visualizes all epitope residues associated with the mAb on to the structure of the DENV E protein. Epitope residues are depicted as spheres, colored according to domain, and with a size corresponding to the epitope resolution, for domain, peptide, and residue-level epitopes.
Whole virus epitope map
Whole virus epitope map description
This whole-virus depiction of the dengue virus envelope maps experimentally identified epitope residues and corresponding predicted quaternary epitopes colored in accordance with three different icosahedral symmetry environments on to the viral surface.

Activity

SpecificityNeutralizingAssay TypeActivity TypeUnitsDENV-1DENV-2DENV-3DENV-4PubMed
Type-specific DENV-2yesBindingIFA, BHK21qualitative-+--7541621

Epitope

MethodEpitope TypeOrganismStrainProteinDomainSequencePubMed
ComputationalPredictedE(AB)65-73,79,81,83-....
PassagingResidueDENV-2New Guinea CED269,7111536239

© 2019 BHSAI
Database last updated on 5 December, 2016.