DENV-Ab DB

Dengue Virus (DENV) Antibody (Ab) Database (DB)

Dengue Virus (DENV) Antibody (Ab) Database (DB) is an online publicly accessible repository for monoclonal dengue antibodies. Each antibody is annotated with respect to source, activity, and epitope information, along with relevant references. DENV-Ab DB contains 410 unique mAbs, 595 activity records, and 545 epitope mapping records.

Reference: Chaudhury, S., G. D. Gromowski, D. R. Ripoll, I. V. Khavrutskii, V. Desai, and A. Wallqvist. Dengue virus antibody database: systematically linking serotype-specificity with epitope mapping in dengue virus. PLOS Neglected Tropical Diseases. 2017 February 21; 11(2):e0005395. [PDF]

mAb List

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Sort

mAb nameFilter by mAb name	Host All Chimpanzee Human Murine	Infection All Primary Secondary	Specificity All Complex Sub-complex Type-specific DENV-1 Type-specific DENV-2 Type-specific DENV-3 Type-specific DENV-4	Epitope Method All Computational Cryo-em Cryptic Peptide Mutagenesis Passaging Pepscan Western blot X-ray Yeast display
1.6D	Human	Primary	Complex	Computational, Mutagenesis
10A1D-2	Murine	Primary	Complex	Western blot
10A4D-2	Murine	Primary	Complex	Western blot
10F2	Murine	Primary	Type-specific DENV-2	Computational, Passaging
13D4-1	Murine	Primary	Complex	Computational, Mutagenesis

Activities | Epitopes |

Composite Epitope Map

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Database last updated on 5 December, 2016.

This research was conducted in conjunction with the Telemedicine and Advanced Technology Research Center (TATRC), Military Infectious Diseases Research Program (MIDRP), and US Army Medical Research and Development Command (USAMRDC).